Resof


QUICK OVERVIEW

Generic Name : Sofosbuvir
Category : Hepatitis Drugs
Company Name : Dr.Reddy's
Dosage Form : 28 Tablets
Strength : 400mg

  

Availability: In Stock

Medicine Overview of Resof


Uses of Resof Tablet


Resof is used to for the treatment of severe Hepatitis C virus in the liver, Resof is highly effective medicine for this infection. Therefore Resof will decrease the action of hepatitis C Virus in our body and recover the liver from infection caused by virus.

Side effects of Resof Tablet


Resof has common and serious effects

Resof in combination with other drugs( ribavirin) along with or without a peg-interferon has a good safety form. Common side effects are fatigue, head pain, nausea, rash in skin  irritability, severe dizziness, back ache, and low RBC.

Serious side effects are accordingly  very common in interferon-containing drugs as compared with interferon-free ones. 

How to use Resof Tablet

Resof is a dose of 400mg.It should take one tablet per day in duration of 12-24 weeks, along with or without food can be taken.

If overdose occurs: Sofosbuvir overdose has no specific antidote available, If it occur patient should monitor  the possible toxicity and provide supportive measure treatment or seek to emergency medical department or call poison control helpline

How to Resof Tablet works:


Resof 400mg  have demonstrated  high barrier resistance and prevents hepatitis C NS5B protein. Its an direct acting antiviral agent which link the different stages of virus cycle (HCV). Resof 400mg interfere with nucleotide protein, by the way it will stops the polymerase enzyme which require for the new reproduction. Resof 400mg by the combination (ribavirin) stimulates the immune response by its own.

Absorption: Time to peak plasma concentration is -0.5 to 2hrs.

Distribution: Protein binding 61% to 65%.

Metabolism: Resof is Metabolized in liver which form pharmacologically active nucleoside and Resof by desphosphorylation leads in formation of nucleoside inactive metabolite GS – 331007.

Excretion: Elimination via urine 80% as metabolite and in feces 14%.

Half life elimination is 0.4 hours.


In Depth Information on Resof Tablet:


Expert Advice for Resof Tablets


  • On treatment of Hepatitis C with Resof will require routine check up  to their physician and blood check up to be followed..
  • Resof should avoided during pregnancy because risk to unborn baby and birth defect occur.
  • Allergic to Sofosbuvir alone, then inform your consultant.
  • Resof combination with amiodarone may cause serious bradycardia.
  • Resof treatment is not recommended in patient with severe kidney and liver disease.

Avoid spreadness of infection via sexual contact, sharing needles or contact with blood during  Resof  400mg treatment


Special Warnings of Resof Tablets


Alcohol

Resof Interaction with alcohol is unknown. If your are alcoholist please consult with doctor.

Pregnancy

Resof pregnancy category B,:In all trimester there are no adequate and well tolerated studies in pregnant women, Since animal reproduction trial has no risks and adverse effect to the fetus. But by combination with ribavirin, assigned a pregnancy category X leads to birth defect and death to the fetus. Avoid combination therapy during pregnancy

Lactation

While breast feeding the drugs pass into breast milk is unknown, therefore its recommended that mother should not breast feed during  Resof  alone and combination treatment.

Driving

Resof  should be given with caution of severe kidney disease in patient. Adjustment of dose require for Resof 400mg Tablet. Please consult your healthcare professional. Information is less available on use of Resof  400mg in this patient and for mild to moderate kidney disease, no dose adjustment required in patient.


Kidney

Resof  should be given with caution of severe kidney disease in patient. Adjustment of dose require for Resof 400mg Tablet. Please consult your healthcare professional. Information is less available on use of Resof  400mg in this patient and for mild to moderate kidney disease, no dose adjustment required in patient.

Liver

Resof 400mg is safe and efficacy in patients with liver disease. Dose adjustment is not required.



Missed Dosage

If you missed a single dose, consult your physician or take it as soon as possible within  next dose reaches. Avoid taking extra or 2 dose at a time. Take doctor advice for further clarification.


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Resof

 
Brand Name : <--------------------> Resof
Category : <--------------------> Hepatitis Drugs
Sub Category :<--------------------> Sofosbuvir
Company Name :<--------------------> Dr.Reddy's
Ingeridents(Generic Name) :<--------------------> Sofosbuvir 400mg
Tablets :<--------------------> 28 Tablets
Package :<--------------------> 1x28
Strength :<--------------------> 400mg

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