Arimidex


QUICK OVERVIEW

Generic Name : Anastrazole
Category : Anti-Cancer Drugs
Company Name : AstraZeneca
Dosage Form : 28 tablets
Strength : 1mg

  

Availability: In Stock

Medicine Overview of Arimidex


Uses of Arimidex Tablet


Arimidex 1mg is a anticancer medication, which is indicated along with other treatment (surgery, radiation) and for treatment of early breast cancer who experienced menopause. The women got first treatment for breast cancer which has been spread within breast or other body areas is also used Arimidex medication.

Arimidex 1mg is used for the treatment in women whose breast cancer got worsened by taking tamoxifen.

Side effects of Arimidex Tablet


The side effects caused by Arimidex 1mg as follows:

Serious side effects:

Hot flashes

Myalagia

Stomach upset

Common side effects:

Loss of energy

Pharyngitis

Hypertension

Weak bones

Fractures

Nausea , vomiting, rash

Sleeping trouble

Dyspnae

How to use Arimidex Tablet

Arimidex 1mg recommended dose In adult is  one tablet of 1mg, taken once a day,

Administrated orally with or without food

Patients having postmenopausal women with hormone receptor +ve  in adjuvant treatment in early invasive breast cancer. Duration of treatment is 5 years.

In pediatric patients. The tablet is not recommended and no insufficient data on safety and efficacy.

How to Arimidex Tablet works:


Anastrazole is a anticancer drugs in which belongs to class of medication called nonsteriodal aromatase inhibitor. It acts by reducing the amount of estrogen in the body.  This will block or slow the growth of many types of tumors which required for estrogen to grow.

Absorption: completely and rapid absorbed from GI tract. Time to peak plasma concentration is 2hours.

Distribution: bounding of human serum protein is 40%

Metabolism: In liver Anastrazole is metabolized through N- dealkylation, hydroxylation and glucuronidation.

Elimination: renal excretion is 10% of total clearance and radiolabeled Anastrazole is recovered via feces and urine is 85%.

Terminal elimination half life of armotraz is 50 hours. 


In Depth Information on Arimidex Tablet:


Expert Advice for Arimidex Tablets


  • Make sure to inform your doctor about any another  drugs  which have been taking (including over-the-counter drugs, vitamins, or herbal remedies) piror to starting of Arimidex 1mg treatment,
  • Arimidex 1mg combine with certain regimen. Make sure to inform your doctor if you are on treatment with these drugs
    • Tamozifen
    • Estrogen
    • Warfarin
    • Estrogen/estradiol-containing medications (commonly used for menopause and birth-control)
  • Piror to starting of Arimidex 1mg treatment, make sure to inform your doctor about health conditions you have previously: cardiac conditions, bone weakness, and abnormal cholesterol.
  • Discuss with your consultant that  you have not had menopause yet (premenopausal).
  • Tell  your health care providers if you are pregnant or may be pregnant prior to starting this treatment. Arimidex 1mg is pregnancy category X which is hazardous to the fetus.
  • Arimidex 1mg excretion into breast milk, the effect is unclear what side effect will be affect on babies. Inform the doctor if you are breastfeeding or plan to breastfeed to their infants.

Special Warnings of Arimidex Tablets


Alcohol

Alcohol interaction with Arimidex 1mg is not known. Please consult the doctor.

Pregnancy

Arimidex 1mg have pregnancy category x have described that animal or human studies shown fetal abnormalities and unsafe to use the drug during pregnancy clearly. Arimidex is contraindicated in pregnant women or to become pregnant

Lactation

Arimidex 1mg is excreted into breast milk taking account on this, discussion should done on whether to discontinue the breast feeding or the drug. Use of drug is contraindicated during breastfeeding. It is unclear the effect of new born babies.

Driving

Arimidex 1mg will affect the ability of driving due to its side effects. Avoid driving unless you feeling well.


Kidney

Arimidex 1mg  used with caution in patients with severe renal disease, dose adjustment is required and limited data is available on the tablets in mild, moderate kidney problem, no dose adjustment is necessary. Please consult doctor.

Liver

 The patient with severe liver disease should Arimidex 1mg with caution. Limited information of the drug in mild to moderate liver disease. No dose adjustment is needed. Please consult with doctor.



Missed Dosage

If you missed a dose take it as soon as possible, if time reach for next dose, then skip missed dose and continue regular schedule. Do not take extra or 2 dose at a time. Please consult with doctor


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Arimidex

 
Brand Name : <--------------------> Arimidex
Category : <--------------------> Anti-Cancer Drugs
Sub Category :<--------------------> Anastrazole
Company Name :<--------------------> AstraZeneca
Ingeridents(Generic Name) :<--------------------> Anastrazole
Tablets :<--------------------> 28 tablets
Package :<--------------------> 2x14
Strength :<--------------------> 1mg

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