Bdenza


QUICK OVERVIEW

Generic Name : Enzalutamide
Category : Anti-Cancer Drugs
Company Name : BRD pharmaceuticals Int'l Pvt Ltd
Dosage Form : 112 tablets
Strength : 40mg

  

Availability: In Stock

Medicine Overview of Bdenza


Uses of Bdenza Tablet


Bdenza 40mg is clinically effective and indicated in the treatment of anti tumor activity of MDV3100 in a phase I/II study of castration resistant prostate cancer.

Side effects of Bdenza Tablet


Bdenza 40mg will causes some side effects.

COMMON SIDE EFFECTS: Body pain; dry throat; dizziness; sleeping trouble; cold symptoms such as stuffy nose; sore throat; Ear congestion; athralagia

SERIOUS SIDE EFFECTS: Epilepsy, fast heartbeat, breathing difficulty, chest discomfort, unusual weigth gain or loss.

How to use Bdenza Tablet

In adult usual dose is 160mg orally

Administrated once in a day has four tablet of 40mg capsule with or without food at same time every day.

Taken as a capsule by mouth, swallow the capsule whole

Do not crush or chew or dissolve capsule.

OVERDOSE OF BDENZA: If overdose occur, will cause seizure. Seek emergency medical attention or call poison helpline.

How to Bdenza Tablet works:


Bdenza 40mg is an anti-androgen drug and it prevents androgen  receptor inhibitor that acts on different stages in the androgen receptor communicating pathway.

Bdenza 40mg has been shown to competitively interfere with androgen linking to androgen receptors and prevents androgen receptor nuclear translocation and interaction with DNA.

A major metabolite, N‑desmethyl enzalutamide, exhibited similar in vitro activity to Bdenza.

Bdenza 40mg reduce proliferation and induced cell death of prostate cancer cells inside the body, and lowers tumor volume in a mouse prostate cancer engrafts model.

ABSORPTION: Bioavailabilty of Bdenza in human is unknown and in rate is 89.7%. peak plasma concentration is 1 hour (range 0.5 to 3 hours).

DISTRIBUTION: Plasma protein binding is 97 to 98% and metabolite N-desmethylenzalutamide

METABOLISM: The drug is metabolite in the liver by CYP2C8 and CYP3A4.

ELIMINATION: Excreted via urine 71.0%, bile in 13.6% and feces in 0.39% Half life is 5.8 days, with range of 2.8 to 10.2 days.


In Depth Information on Bdenza Tablet:


Expert Advice for Bdenza Tablets


  • Another medications which involves in prescription, over-the-counter, vitamins, herbal remedies, etc.and avoid Aspirin, or products related to aspirin your consultants  permits this specifically. Inform your doctor before use of Bdenza 40mg
  • While administrating  Bdenza avoid  any kind of immunization or vaccination until doctor’s approval
  • Inform your Consltants if you are pregnant or planning to  pregnant before  starting the treatment.
  • Due to severe adverse reactions in the new born baby, breast-feeding is not recommended.

Special Warnings of Bdenza Tablets


Alcohol

Alcohol interaction with Bdenza 40mg is unknown. Please consult with doctor.

Pregnancy

In animal reproduction studies, there is a adverse effect for fetal, hence no human data on the use of Bdenza 40mg in pregnancy. Bdenza is contraindicated in women during pregnancy and cause fetal death and potential loss of pregnancy

Lactation

Bdenza 40mg is not recommended to use in females. There is no information available in presence of Bdenza in human milk. The effects in the nursing infants are unknown.

Driving

While taking the Bdenza 40 mg dizziness occurs, It will affect the ability of driving. Avoid driving unless you feeling well.


Kidney

When patients with mild ,moderate kidney disease no adjustment recommended  in Bdenza 40mg. Patients with severe kidney problem or ESRD use with caution is recommended.

Liver

Bdenza 40mg has no dosage adjustment is necessary in mild or severe renal impairment. Caution recommended in moderate liver disease in patients.



Missed Dosage

If you missed a dose take it as soon as possible, if time reach for next dose, then skip missed dose and continue regular schedule. Do not take extra or 2 dose at a time.


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Bdenza

 
Brand Name : <--------------------> Bdenza
Category : <--------------------> Anti-Cancer Drugs
Sub Category :<--------------------> Enzalutamide
Company Name :<--------------------> BRD pharmaceuticals Int'l Pvt Ltd
Ingeridents(Generic Name) :<--------------------> Enzalutamide
Tablets :<--------------------> 112 tablets
Package :<--------------------> 4X28
Strength :<--------------------> 40mg

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