Medicine Overview of Hepcinat Tablet
Uses of Hepcinat Tablet
Hepcinat is used to for the treatment of severe Hepatitis C virus in the liver, Hepatitis C virus is a long lasting infection of liver, Hepcinat is highly effective medicine for this infection. Therefore it will decrease the action of hepatitis C Virus in our body and recover the liver from infection caused by virus.
Side effects of Hepcinat Tablet
Changes in mood
Low red blood cell
Fever and chills
How to use Hepcinat Tablet
Dose recommended for Hepcinat medication is one tablet of 400mg OD (once daily) taken orally given along with food or without . HepcinatÂ Duration for genotype 1 or 4Â and 2 (CHC) is 12 weeks and Genotype 3 (CHC) is 24 weeks.
If overdose occurs: Sofosbuvir overdose has no specific antidote available, If it occur patient should monitorÂ the possible toxicity and provide supportive measure treatment or seek to emergency medical department or call poison control helpline.
How to Hepcinat Tablet works:
Hepcinat is a nucleotide polymerase inhibitor and includes in direct acting antiviral drug. Hepcinat expose to have a high barrier to the development of resistance and inhibits the hep C NS5B protein. Thereby Hepcinat prevents the enzyme RNA polymerase by the cellular worker who can performs the multiplication process, Hence Hepcinat stops the replication of Hepatitis CÂ virus and decrease the amount of Hep C virus in liver. Hepcinat also acts to reduce damage in liver and improves function in liver
Absorption: Time to peak plasma concentration is -0.5 to 2hrs.
Distribution: Protein binding 61% to 65%.
Metabolism: Metabolized by hepatic, It form pharmacologically active nucleoside analog triphosphate GS-461203; by desphosphorylation results in formation of nucleoside inactive metabolite GS â€“ 331007.
Excretion: Elimination via urine 80% as metabolite and in feces 14%.
In Depth Information on Hepcinat Tablet:
Expert Advice for Hepcinat Tablets
- On treatment of Hepatitis C with Hepcinat will require routine check upÂ to their physician and blood check up to be followed..
- Hepcinat should avoided during pregnancy because risk to unborn baby and birth defect occur.
- Allergic to Sofosbuvir alone, then inform your consultant.
- Hepcinat combination with amiodarone may cause serious bradycardia.
- Hepcinat treatment is not recommended in patient with severe kidney and liver disease.
- Avoid spreadness of infection via sexual contact, sharing needles or contact with blood during Sofovir 400mg treatment
Special Warnings of Hepcinat Tablets
Hepcinat interaction with alcohol is unknown. If your are alcoholist please consult with doctor.
Pregnancy category B:In all trimester there are no adequate and well tolerated studies in pregnant women, Since animal reproduction trial has no risks and adverse effect to the fetus. But by combination with ribavirin, assigned a pregnancy category X leads to birth defectÂ and death to the fetus. Avoid combination therapy during pregnancy
While breast feeding the drugs pass into breast milk is unknown, therefore its recommended that mother should not breast feed during Hepcinat alone and combination treatment.
Hepcinat when taken combination with other medicine for the treatment of hepatitis C, It will cause blurred vision ,dizziness and affect the ability to drive. Avoid driving if you are not feeling well.
Hepcinat should be given with caution of severe kidney disease in patient. Adjustment of dose require for Sofovir 400mg Tablet. Please consult your healthcare professional. Information is less available on use of Hepcinat400mg in these patient and for mild to moderate kidney disease, no dose adjustment required in patient.
Hepcinat 400mg is safe and efficacy in patients with liver disease. Dose adjustment is not required. MISSED DOSE
If you missed a single dose, consult your physician or take it as soon as possible within next dose reaches. Avoid taking extra or 2 dose at a time.
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Category: --------------------Hepatitis Drugs
Sub Category:-------------------- Sofosbuvir
Brand name:-------------------- Hepcinat
Ingeridents(Generic Name) :-------------------- Sofosbuvir 400mg
Package:-------------------- 28 Tablets/1x28
Strength :-------------------- 400mg