Dacihep


QUICK OVERVIEW

Category : Hepatitis Drugs
Sub Category : Daclatasvir
Brand name : Dacihep
Generic Name : Daclatasvir
Company Name : Hetero
Tablets : 28 Tablets / Package : 3x28
Strength : 60 mg

  

Availability: In Stock

Medicine Overview of Dacihep Tablet


Uses of Dacihep Tablet


Dacihep 60 mg is used with other antiviral agent for the treatment  of chronic Hepatitis C virus ( viral infection of liver which will long last in the body). It will cause serious liver problem(cirrhosis, liver cancer).

Dacihep 60mg tablet Combination with Sofosbuvir reduce the bulk of Hepatitis virus in the body, in which it will help to fight against infection free immune system and clear the liver.

Side effects of Dacihep Tablet


 Common side effects of dacihep 60mg

  • Loss of hair
  • Low RBC
  • Loose stools
  • Vomiting
  • Dizziness
  • Feeling sleepy in morning
  • Head pain
  • Dullness
  • Itching/swelling(face, tongue,throat)

   Serious side effects of dacihep 60mg

  • Chest discomfort
  • Dyspnea
  • Loss of memory
  • Unusual weight gain or loss
  • Low heartbeats
  • Lethargy
  • Arthalgia
  • Myalgia

How to use Dacihep Tablet


The doctor prescribe the Dacihep 60 mg based on age, past medical history and current status of diagnosis.

 When combination with Sofosbuvir the dose recommended is one tablet of 60mg taken once in a day by oral route with or without food.

Duration of treatment12weeks

Modification of dose :  Reduce 30mg OD for strong CYP3A leads no  Dose reduction. Increase dose to 90mg OD with moderate                                     CYP3A leads to contraindicated.

For genotype 1 or 4 : treatment with daclatasvir +ribavirin+ peg IFN for 12 weeks

For genotype 2 : treatment with daclatasvir + ribavirin for 12 weeks

For genotype 3: treatment with daclatasvir + ribavirin (without interferon) for 24 weeks.

OVERDOSAGE: Dacihep 60mg overdose has no particular antidote. Treatment will consist of supportive measures, involving monitoring of vitals and patient clinical status observation

How to Dacihep Tablet works:


Hepatitis means person affected by hepatitis C virus and target the liver, thus became inflate. Due to longer stay of virus in the body leads to severe damage to the liver occurs. It is a CYP3A and p- glycoprotein. Daclatasvir attack the virus,and stops the process of multiplication and replication of  the HCV. Here by drug will prevents the virus particle duplication by its own and removes the virus from the body.

Absorption: Poor absorption, peak plasma concentration is 2 hours post dose and bioavailability is 67%

Distribution: while multiple dosing, plasma protein binding is 99%, on dialysis it significantly decrease the plasma binding and vol of distribution is 47L

Metabolism: Daclatasvir is primarily metabolized through CYP3A4

Elimination: Daclatasvir excreted through feces of  (88%,53% unchanged) ; urine (6.6% primarily unchanged).

Terminal half life elimination is 12 – 15 hours.


In Depth Information on Dacihep Tablet:


Expert Advice for Dacihep Tablets


  •  Tell your healthcare providers that you are allergic to daclatasvir or  have any other allergies before using the medicine. It may composed of inactive ingredients, that can  be cause allergic problems or other reaction. Talk to your pharmacist for more details.
  •  Especially if you have kidney disease, liver disease other than hepatitis C, inform your consultant about past medical history before having daclatasvir.
  • Drugs should given with prescription only, without prescription drugs should not be issued.


Special Warnings of Dacihep Tablets



Alcohol


There is no data available for Dacihep 60mg. Please consult your doctor

Pregnancy


Pregnancy category for dacihep 60mg is not predicted, when oral dose the animal studies have failed to explain the signs of fetal harm. There are no controlled data in human pregnancy. This drug should use with combination of other antiviral drug. Use of ribavirin containing regimen is contraindicated in pregnant women and the male partner. For some authorities, this drug should avoid during pregnancy.

Lactation


Low amount of this drug  in breast milk as DaciHep 60mg is highly bound to maternal plasma protein, If the drug require for the feeding mother and it is not a reason for discontinue breastfeeding, If the drug using with ribavirin avoid breast feeding

Driving


While taking Dacihep 60mg  you will feel dizziness, difficulty in concentrating and vision problem this may affect your driving. So avoid driving till you feeling well.



Kidney


Dacihep 60mg has no dosage adjustment recommended with renal dysfunction. Please consult with your doctor

Liver


Mild, moderate or severe liver dysfunction has no dose adjustment recommended by using dacihep 60mg. Please consult with your doctor.



Missed Dosage


As soon as you remember take the missed dose. If time for next dose then skips the missed dose and follow the routine scheduled. Do not take more than one tablet per day. Please consult your doctor for further details



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Dacihep

 
Category: --------------------Hepatitis Drugs
Sub Category:-------------------- Daclatasvir
Brand name:-------------------- Dacihep
Ingeridents(Generic Name) :-------------------- Daclatasvir
Package:-------------------- 28 Tablets/3x28
Strength :-------------------- 60 mg

GOOD QUALITY PRODUCTS


FREE SHIPPING FOR 12 WEEKS OF HEPATITIS DRUGS BY EMS

ONLINE/OFFLINE SUPPORT 24/7


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