Erlocip


QUICK OVERVIEW

Category : Anti-Cancer Drugs
Sub Category : Erlotinib
Brand name : Erlocip
Generic Name : Erlotinib
Company Name : Hetero
Tablets : 30 TABLETS / Package : 1X30
Strength : 150mg

  

Availability: In Stock

Medicine Overview of Erlocip Tablet


Uses of Erlocip Tablet


Erlocip 150mg mainly prescribed  for non- small lung cancer and pancreatic cancer.

Non-small lung cancer: Erlocip preferred has first line therapy in patient with NSCLC in which there disease have no progressed after 4cycles of platinum-based first line chemotherapy.

Pancreatic cancer: Erlocip used with combination of gemcitabine for the first line therapy in patient with advance metastatic pancreatic cancer.

Side effects of Erlocip Tablet


Erlocip 150mg  major side effects:

  • Dry eyes

  • Vomiting and nausea

  • Stomach discomfort

  • Diarrhea

  • Dry skin

  • Loss of appetite

  • Mouth sores

  • Weakness

Contact a doctor immediately encounters more severe side effects such as:

  • Easy bleeding

  • Yellow colour  in skin or eyes

  • Unusual fatigue

  • Signs of infection

  • Black, bloody or tarry stools and dark urine

  • Eye irritation or pain

  • Vision or speech problems

  • Shortness of breath

  • Chest pressure

  • Vision problem

  • Confusion

How to use Erlocip Tablet


Erlocip  is administer in tablet form to be consume by mouth at least one hour before or two hours after eating. The tablets are supplied in 25mg, 100mg and 150mg strengths.

Non-small cell lung cancer: Analysing of EGFR mutation testing before Erlocip  treatment. Dose prescribed 150mg one tablet  taken 1hour or 2 hour after the meal.

Pancreatic cancer: Erlocip dose of 100mg combination with gemcitabine ( 1hr or 2hr after the meal). Requirement of dose adjustment  to reduce in 50mg steps.

Erlocip tablet used on an empty stomach 1hr before or 2hr after the digestion of food. Swallow the tablet via orally. Avoid concomitant use of proton pump inhibitor with Erlocip  tablet.

Hepatic impairment:  Based on severe adverse reaction occurs the dose reduction of Erlocip is studied in patient with severe hepatic impairment.

Erlocip exposure will be reduced in cigarette smoking patient

If any gastric problem with Erlocip then take it 10 hrs after H2 receptor or before 2hrs of next antacid dose

Safety and efficacy has not established in renal impairment, pregnancy use.

In pediatric: Safety and efficacy is not established <18years.

IF OVERDOSAGE OCCURS: Erlocip with overdose the symptoms of diarrhea, rash and liver transminase elevation occurs then urgent symptomatic and supportive treatment required.

How to Erlocip Tablet works:


          In the body, certain cells  grow and multiply in a way that is 'out of control' means cancer. Erlocip interfere with the cells grow and increase in number. Erlocip works by preventing certain enzymes called tyrosine kinases that are needed for the transmitting the chemical signals which is require for essential processes like cell division and replication in cancer cells. Which in turn Erlocip blocks the cancer cells from growing and increasing in number.

          ABSORPTION: Erlocip 60% absorbed and  bioavailability is subsequently increased by food (100%). Peak  plasma level about 4 hours after dosing.

            DISTRIBUTION: Erlocip  bounded to plasma albumin protein and alpha-1acid glycoprotein is approximately 93%.

            METABOLISM: Erlocip 150 mg tablet mainly metabolized by CYP3A4 and to a lesser action by CYP1A2, and the extrahepatic isoform CYP1A1. Steady state plasma concentration of Erlocip is about 7-8 days.

             EXCRETION: Erlocip eliminated in feces 83%  and 8% in urine and half life of 36.2 hours.91% is recovered dose.


In Depth Information on Erlocip Tablet:


Expert Advice for Erlocip Tablets


  •  If you are allgeric to the Erlocip or any other medicine, immediately inform your doctor.
  • While taking Erlocip,Inform your doctor about previously taking medicine involved in prescription and non prescription, over the counter, vitamins, herbal, nutritional supplements.
  • Antacid should consume several hours before and after the drug Erlocip.
  • On treatment of  Erlocip, avoid becoming pregnant for a month after final dose. Consult with doctor because Erlocip may affect the fetus.
  • Due to use Erlocip, skin problem occurs for protection use mild alcohol free moisturizer.

On Erlocip treatment avoid grapefruit or grapefruit juice


Special Warnings of Erlocip Tablets



Alcohol


While taking Erlocip150mg, alcohol interaction is unknown. Please consult with doctor.

Pregnancy


     Based on side effects there is positive evidence of human fetal risk In pregnant women use of Erlocip 150mg may be gain acceptable against the risk means if the drug is used in a life-threatening situation are ineffective.

Lactation


On treatment with Erlocip 150mg, breastfeeding is not recommended because unknown reason in animal milk and affects the nursing infants.

Driving


Erlocip 150mg  tablet alters the ability to drive is unknown. If you experience any symptoms that affect your ability to concentrate then avoid driving unless you feeling well



Kidney


Erlocip 150mg tablet is safe to use with kidney problem patients. No dose adjustment is required. In severe kidney disease patient’s use of Erlocip is not advisable.

Liver


No dosage adjustment required in patients with baseline mild liver disease. Avoid using of Erlocip 150mg while patients with baseline severe hepatic impairment . Dose adjustment may be required. Please consult with your doctor.



Missed Dosage


The drug dose is missed, then take the drug dose as soon as possible. If next dose time arrived then skip the missed dose and continue the routine schedule. Avoid taking extra dose or 2 dose at one time. Please consult your doctor for further clarification



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Erlocip

 
Category: --------------------Anti-Cancer Drugs
Sub Category:-------------------- Erlotinib
Brand name:-------------------- Erlocip
Ingeridents(Generic Name) :-------------------- Erlotinib
Package:-------------------- 30 TABLETS/1X30
Strength :-------------------- 150mg

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