Gefinat


Special Price $ 132

Regular Price: $ 137

QUICK OVERVIEW

Category : Anti-Cancer Drugs
Sub Category : Geftinib
Brand name : Gefinat
Generic Name : Geftinib
Company Name : Hetero
Tablets : 30 TABLETS / Package : 1X30
Strength : 250mg

  

Availability: In Stock

Medicine Overview of Gefinat


Gefinat Description


Geftinat 250mg is a drug used   for the treatment of certain types of cancer. Acting in a same manner to erlotinib ,

Geftinat 250mg specifically binds  the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.

Geftinat 250mg is classified by signal transduction inhibitor i.e EGFR tyrosine kinase inhibitor.


Uses of Gefinat


 Geftinat 250mg is an anticancer drug which is indicated for the treatment of metastatic non-small cell lung cancer after failure of both platinum and taxane based chemotherapies.

Side effects of Gefinat


Common side effects in  Geftinat 250mg (occurring in greater than 30%):

   Loose stools; skin reaction

Less common in  Geftinat 250mg (occurring in about 10-29%):

  • Nausea
  • Vomiting
  • Itching
  • Poor appetite
  • Eye irritation

How to use Gefinat


Geftinat 250mgis a form of  tablet which taken  by mouth. It is administrated with or without food once a day.

Recommeded dose of adult is 250mg.Take gefitinat at  same time every day.

Take Geftinat 250mgexactly as directed. Avoid taking  more or less or consume based on doctor’s advice.

If patient is not able to swallow the tablets, tablet may dissolve them in water. Take  one tablet in 120 to 240 ml of plain, noncarbonated drinking water. 15 minutes  require until the tablet is dissolved and use spoon to stir it.

Drink the mixture immediately. Rinse the glass with another 4 to 8 ounces of water and drink the rinse water completely to be sure that you swallow all of the drug.

 Doctor may delay or permanently stop the treatment if you feel certain side effects. Inform your doctor when you feel difference after taking medication.

OVERDOSAGE: Geftinat has no specific treatment for the overdose.an increase of dose frequency and severity of some adverse reaction was observed like diarrhea and skin rash.

How to Gefinat works


EGFR is a kind of protein found on the surface of cells in your body. Mutated EGFR plays a part in cancer growth by sending out signals that make the cells grow and divide.

But Geftinat 250mg may make a difference for you.attaches itself to certain abnormal types of the EGFR protein on your lung cancer cells. By doing so, it has been shown to slow down the growth of these cells and may help reduce the size of your tumors.

ABSORPTION: slow absorbed from GI tract, the  bioavailability shows of approx 60% and peak plasma concentration time is 3-7hr.

DISTRIBUTION: volume of distribution in Geftinat is 1400L and plasma bounding is approx 90%.

METABOLISM: Geftinat 250mgmetabolized by hepatic via CYP3A4 and CYP2D6. It has major metabolites is o-desmethylgeftinib.

ELIMINATION: Geftinat 250mg eliminated through  faeces (86%) and urine (<4%) and terminal half life is 41-48 hr.

In Depth Information on Gefinat


Expert Advice for Gefinat


  If you are allergic to Geftinat 250mg, avoid using the medicine.

To known about gefitinib is safe for you, inform the  doctor if you have:

  • hepatocellular disease
  • Renal disease;
  • Problems in visions.
  • Dyspnea , lung disease other than lung cancer or
  • Under treatment of blood thinner (warfarin, coumadin, Jantoven)

Avoid use of Geftinat 250mg if you are pregnant. It will harm the baby unborn, while using Geftinat 250mguse correct birth control to prevent pregnancy and for at least 2 weeks after your treatment ends. Geftinat 250mg may affect the ability to have children in women. Inform your doctor if you planning to pregnant.

It is  unknown whether Geftinat 250mg passes into breast milk , avoid breast-feed while on gefitinib treatment.


Special Warnings of Gefinat

Alcohol


Alcohol interaction with Geftinat 250mg is unknown. Please consult with the doctor.

Pregnancy


Category D: Geftinat 250mg show  human fetal risk, but the use in pregnant women may be occur even with the risk . It is ineffective  while the drug needed for life threatening situation.

Lactation


In animal studies show that the drug and metabolite is present in milk of lactating rats. Hence while on treatment discontinue the breast feeding

Driving


Avoid driving unless you feeling well, while treatment with Geftinat 250mg you will feel dizzy, weekness and It affects the ability to drive.



Kidney


Geftinat 250mg tablet  should be used with caution in severe kidney problem patients. Ose adjustment is need. Please consult with the doctor

Liver


Geftinat 250mg is safe to use in patients with liver disease, limited data available. Dose adjustment may not be needed. Please consult with the doctor.



Missed Dosage


If you missed a dose take it as soon as possible, if time reach for next dose, then skip missed dose and continue regular schedule. Do not take extra or 2 dose at a time. Please consult with doctor.



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Gefinat

 
Category: --------------------Anti-Cancer Drugs
Sub Category:-------------------- Geftinib
Brand name:-------------------- Gefinat
Ingeridents(Generic Name) :-------------------- Geftinib
Package:-------------------- 30 TABLETS/1X30
Strength :-------------------- 250mg

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