MyHep-MyDekla


QUICK OVERVIEW

Category : Hepatitis Drugs
Sub Category : Sofosbuvir-Daclatasvir
Brand name : MyHep-MyDekla
Generic Name : Sofosbuvir 400mg & Daclatasvir 60mg
Company Name : Hetero
Tablets : 28 Tablets / Package : 3x28
Strength : 400mg &60mg

  

Availability: In Stock

Medicine Overview of MyHep-MyDekla Tablet


Uses of MyHep-MyDekla Tablet


Myhep plus Mydekla is used for the treatment of chronic hepatitis C virus (HCV) genotype 1 or 3 infection with or without ribavirin.

Side effects of MyHep-MyDekla Tablet


When Myhep and Mydekla adminstrating of combination with amiodarone will cause some side effects on heart and seek medical help if you have:

Slow heartbeat

Shortness of  breath , Chest discomfort

Lightheadness

Serious side effects:

Decreased  appetite

Low RBC

Infection like sore throat

Loss of Memory and confusion

Severe vertigo

Severe weakness

Common effects:

Diarrhea

Muscle pain

depression

Head pain

Triedness.

How to use MyHep-MyDekla Tablet


 In adult recommended dosage of Myhep is 400 mg and Mydekla is 60 mg.Both drugs administrated through orally, once in a day.

Given with or without food.

For genotype 1

Myhep plus Mydekla without cirrhosis  or with compensated cirrhosis   ( child-pugh A)for 12weeks. Myhep , Mydekla and ribavirin combination  is used  for decompensated cirrhosis  (child – pugh B or C) and Posttransplant

For genotype 3

Daclatasvir  plus Sofosbuvir without cirrhosis for 12weeks. Myhep , Mydekla  and ribavirin combination used for compensated or decompensated ( child-pugh B or C) cirrhosis and Posttransplant for 12weeks.

      Overdose of Myhep and Mydekla: No specific antidote available, If overdose occur, patient should be monitor the development of toxicity and supportive and symptomatic care should be monitor. Seek medical emergency or call poison control for immediate treatment

How to MyHep-MyDekla Tablet works:


 Mydekla  is a direct acting antiviral drug which is indicated for the patient affected by hepatitis c virus infection. It will targets the Hep C virus and stops the numerous steps in reproduction process of HCV by the way it interfere with the virus particles from making copies themselves, and  helps the body to remove virus  from the blood.

Myhep is a nucleotide polymerase inhibitor and includes in direct acting antiviral drug. Myhep expose to have a high barrier to the development of resistance and inhibits the hep C NS5B protein and It will inhibits the RNA polymerase enzyme by the cellular worker who can performs the multiplication process, Hence it stops the replication of Hepatitis C virus and decrease the amount of Hep C virus in liver. Myhep also acts to reduce damage in liver and improves function in liver

  Absorption:- Myhep peak plasma concentration of obtained at -0.5 to 2 hr post dose and in metabolite GS-331007 peak plasma concentration  obtained between 2 to 4 hrs post dose, where as In Mydekla peak plasma concentration is within 2 hours post dose and bioavailability is 67%

Effect of food: Myhep and the metabolite have no affect with high fat meal. Hence Myhep is administrated without food is effective. In Mydekla drug either  taken with food  nor without food.

Distribution: Myhep is approx 51-65% bound to human plasma proteins and GS-331007 metabolite has minimal human plasma protein binding. And in Mydekla , the plasma protein binding is 99%

Metabolism:  Myhep is broadly metabolized in liver (4% and >90%) to convert into pharmacologically active nucleoside analog triphosphate GS-461203. Mydekla metabolism based on the substrate of CYP3A with primry CYP isoform

Elimination:  Myhep elimination in urine 80%, feces 14% and 2.5%expired air. While single dose administration of Mydekla, elimination of radioactivity was recovered 88% via feces and 6.6% via urine

Half life of Myhep and GS-331007 were 0.4 and 27hrs and Mydekla has  half life elimination of 12 to 15 hours


In Depth Information on MyHep-MyDekla Tablet:


Expert Advice for MyHep-MyDekla Tablets


  • Combination of Myhep, Mydekla and amiodarone may cause bradycardia
  • Drugs should given with prescription only, without prescription drugs should not be issued.
  • Inform your healthcare providers that you are allergic to daclatasvir ,Sofosbuvir or  have any other allergies before using the medicine. It may composed of inactive ingredients, that can  be cause allergic problems or other reaction. Talk to your pharmacist for more details.
  •  Especially if you had any  kidney disease, liver disease other than hepatitis C, inform your consultant about past medical history before having daclatasvir / sofosbuvir

Special Warnings of MyHep-MyDekla Tablets



Alcohol


Alcohol interaction with Myhep plus Mydekla combination is unknown. Please consult with doctor.

Pregnancy


Pregnancy category B for Myhep plus Mydekla combination, In all trimester there are no adequate and well tolerated studies in pregnant women, Since animal reproduction trial has no risks and adverse effect to the fetus. But  with ribavirin combination,pregnancy category X cause to birth defect  and death to the fetus. Avoid combination therapy during pregnancy.

Lactation


Myhep plus Mydekla excreted into human milk is unknown, therefore its recommended that mother should not breast feed during Myhep plus Mydekla combination treatment.

Driving


While using Myhep plus Mydekla combination you may get dizziness, weakness and confusion and make tried. So avoid driving until you feeling well. Please consult with doctor.



Kidney


No dosage adjustment recommended with mild , moderate kidney problem and limited information about this drug. So please consult with doctor and inform him before taking Myhep plus Mydekla tablet.

Liver


Myhep plus Mydekla administration, patients with mild , moderate and severe dysfunstion has no dosage adjustment. Please consult with your doctor.



Missed Dosage


If you missed a dose take it as soon as possible, if time reach for next dose, then skip missed dose and continue regular schedule. Do not take extra or 2 dose at a time. TAKE ADVICE FROM THE DOCTOR.



Customer Reviews

Amazing Review by Millionpharma

No Customer Reviews

(Posted on )

Write Your Own Review

1 star 2 stars 3 stars 4 stars 5 stars
Quality
Price
Value

MyHep-MyDekla

 
Category: --------------------Hepatitis Drugs
Sub Category:-------------------- Sofosbuvir-Daclatasvir
Brand name:-------------------- MyHep-MyDekla
Ingeridents(Generic Name) :-------------------- Sofosbuvir 400mg & Daclatasvir 60mg
Package:-------------------- 28 Tablets /3x28
Strength :-------------------- 400mg &60mg

GOOD QUALITY PRODUCTS


FREE SHIPPING FOR 12 WEEKS OF HEPATITIS DRUGS BY EMS

ONLINE/OFFLINE SUPPORT 24/7


We Are Deals with,

Image
Image
Image
Image
Image
Image
Image
Image