Medicine Overview of Lenalid-25mg Tablet
Uses of Lenalid-25mg Tablet
Lenalid 25mg is indicated for the treatment of multiple myeloma, Myelodysplastic syndrome and mantle cell lymphoma.
Side effects of Lenalid-25mg Tablet
Commonly reported side effects of lenalid include:
Shortness of breath, nose bleeding,swelling in bone, head pain, low level in potassium, fatigue,insomnia, limb pain, muscle cramps, nasopharyngitis, nausea, peripheral edema, pharyngitis, pruritus, skin rash, vomiting, anorexia, and xeroderma, , abdominal pain, anemia, arthralgia, asthenia, back pain, constipation, cough, diarrhea, dizziness,
Other side effects include:
Deficiency in WBC, diarrhae, muscle pain, low in BP,magnesium level,thyroid levels, fast heart beating, peripheral neuropathy, rhinitis, upper abdominal pain, bruise, diaphoresis, dyspepsia, ecchymoses, erythema, and xerostomia. febrile neutropenia, cellulitis, chest pain, depression,difficulty in urine, hypoesthesia, increased serum alanine aminotransferase ,night sweat
How to use Lenalid-25mg Tablet
In adult dose:
For Myelodysplastic disease:10mg orally once daily
For Multiple Myeloma: with dexamethasone combination taken 25 mg orally once daily on days 1- 21 of 28 day repeated cycles.
For lymphoma:25 mg orally once daily on days 1-21 days of repeated 28 days cycle
Swallow the whole medicine with one glass of water, do not chew or crush it.
Lenalid 25mg taken with or without food.
Overdosage: Lenalid has no specific antidote for the overdose. If it occurs seek to emergency department or call poison control helpline.
How to Lenalid-25mg Tablet works:
Lenalid 25mg is an immunomodulatory agent with antiangiogenic and antineoplastic property. It prevents proinflammatory cytokines secretion, develop the interleukin-2 and interferon-γ secretion, and increases cytolytic T-cell and natural killer cell response. Lenalid interferes with the growth of myeloma cells by activating cell cycle arrest and cell breakdown.
Absorption: well absorbed. Time to peak plasma concentration: Approx 0.6-1.5 hr. Absorption extent may be decreased by high-fat and high-calorie meal.
Distribution: Small amount of semen is present in Lenalid. Plasma protein binding: Approx 30%.
Metabolism: Poorly metabolised.
Excretion: Elimination through urine (approx 66% as unchanged drug). Elimination half-life: 3-5 hr.
In Depth Information on Lenalid-25mg Tablet:
Expert Advice for Lenalid-25mg Tablets
While taking lenalid 25mg,Inform your doctor about previously taking medicine involved in prescription and non prescription, over the counter, vitamins, herbal, nutritional supplements.
With lenalid 25mg avoid taking aspirin, or products containing aspirin until doctor specifically permit may decrease the effectiveness of this medication.
Acetominophen (Tylenol®) may not be recommended. Inform your doctor .
Kindly discuss with health care professional if you are pregnant or chance of to be pregnant before starting this treatment.
For pregnant women and partner man: Avoid a chance of conceive a child (get pregnant) while on treatment with Lenalid. Barrier methods of contraception, such as condoms, are recommended. Discuss with your consultants , it will be safe to become pregnant or conceive a child after treatment.
Avoid breast feeding while on medication therapy.
Special Warnings of Lenalid-25mg Tablets
Alcohol interaction to Lenalid 25mg is unknown. Please consult with the doctor.
Category x: In pregnancy , there is a evidence of fetal risk on both human and animal. The use of drug in pregnant is risk clearly. the drug is contraindicated to pregnant women.
Lenalid 25mg tablets are possiblely unsafe during breastfeeding. The drug will affect risk to the infants. Please cosult with doctor before the treatment.
Lenalid 25 mg has a side effects of vertigo, sleepy and blurred vision, it may affect the ability of driving. Avoid driving unless you feeling well.
Lenalid 25mg should be used with caution in patients having kidney disease dose adjustment is needed. Please consult with doctor before the treatment.
Lenalid 25mg should be used with caution in patients having hepatic disease, dose adjustment may be necessary. Please consult with doctor before the treatment.
The drug dose is missed, then take the drug dose as soon as possible. If next dose time arrived then skip the missed dose and continue the routine schedule. Avoid taking extra dose or 2 dose at one time. Please consult your doctor for further clarification
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Brand Name : <--------------------> Lenalid-25mg
Category : <--------------------> Anti-Cancer Drugs
Sub Category :<--------------------> Lenalidomide
Company Name :<--------------------> Natco pharma Ltd
Ingeridents(Generic Name) :<--------------------> Lenalidomide
Dosage Form :<--------------------> 30 capsules
Package :<--------------------> 1X30
Strength :<--------------------> 25MG